Background

Prima Donna targets enamel erosion, an irreversible condition that increases with age and drives major oral disease burden. The program uses induced pluripotent stem cell techniques to generate enamel-regenerating organoids and advance toward animal-model validation.

Scientific Approach

The team reported enamel-like material production in a living organism and is now focused on scale-up and translational validation steps. This positions the project beyond purely symptomatic interventions like veneers or crowns.